Antibiotrophy: Key Function for Antibiotic-Resistant Bacteria to Colonize Soils—Case of Sulfamethazine-Degrading Microbacterium sp. C448

Draft Genome Sequence of the Sulfonamide Antibiotic-Degrading Microbacterium sp. Strain C448

We report the draft genome sequence of Microbacterium sp. strain C448, isolated from agricultural soil with a decade of exposure to veterinary antibiotics on the basis of using sulfamethazine and other antibiotics as the sole sources of carbon. The genome sequence revealed that strain C448 harbors several antibiotic resistance genes, including sulI.

Microbacterium oleivorans sp. nov. and Microbacterium hydrocarbonoxydans sp. nov., novel crude-oil-degrading Gram-positive bacteria.

A taxonomic study of two crude-oil-degrading, Gram-positive bacterial strains, designated BAS69(T) and BNP48(T), revealed that they represent two novel Microbacterium species. 16S rRNA gene sequence similarity to their closest phylogenetic neighbours was 98.5 % for BAS69(T) (Microbacterium paraoxydans DSM 15019(T) and Microbacterium saperdae DSM 20169(T)) and 99 % for BNP48(T) (Microbacterium l...

SCREENING FOR ANTIBIOTIC RESISTANT BACTERIA IN URINE SAMPLES

Chronic urinary tract infections are often caused by antibiotic resistant bacteria. In some of these cases, prediction of the most effective antibiotic (s) may urgently be needed. This can not be achieved unless the nature and patterns of the resistance to antibiotics among the pathogenic bacteria has been described earlier. The urine samples that reached the laboratory of Shaheed Mustafa K...

Impacts of Antibiotic-Resistant Bacteria

New antibiotics for antibiotic-resistant bacteria

The need for new antibiotics to effectively treat antibiotic-resistant infections remains unfulfilled. Despite the well-publicised concern over this issue, only two novel antibiotic classes have been introduced in the past 20 years alongside several new agents of existing classes. Accordingly, the current antibiotic armoury remains inadequate to meet the challenges posed by resistance today. Mo...